• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    A device for use in treating pectus excavatum is described, comprising: a guide (1) with at least one support body (6) to rest on the sternum (2) of a patient (3) with a deformation of pectus excavatum ; and two curved channels (8); at least one hollow needle (4), curved in correspondence with the channels (8), to be inserted through one of the channels (8) and extracted by the other channel (8), passing through the sternum (2) inside, without going through the sternum (2), and causing an insertion in the sternum (2), to house a wire (9) along the insert, intended to raise and stabilize the sternum (2) correcting the deformation; and a correction bar (10), intended to be inserted laterally at the subcutaneous level above the sternum (2) once the wires are tensioned, to sand the wires (9) to the bar (10). The device is less invasive than other techniques, such as the Ravitch technique, the Nuss technique, and Taulinoplasty. (Machine-translation by Google Translate, not legally binding)
    公开号:ES2777423A1
    申请号:ES201931102
    申请日:2019-12-11
    公开日:2020-08-04
    发明作者:Gil Jorge Gutierrez；San Roman Carlos Gutierrez
    申请人:Gil Jorge Gutierrez；
    IPC主号:
    专利说明:

    [0004] Technical field
    [0006] The present invention can be included in the technical field of medicine and surgery. More specifically, the object of the invention refers to a device intended to be used in the treatment of cases of thoracic malformations with sunken chest ( pectus excavatum).
    [0008] Background
    [0010] Pectus excavatum PE (sunken chest or funnel chest) is the most common congenital malformation of the thoracic wall, with an approximate incidence of 1 in 1000 live births, with a distribution three times higher in the male population. It consists of a deformity of the rib cage, and is characterized by a sinking of the chest in the region of the sternum and ribs. Sternal subsidence is not only an aesthetic problem, as it sometimes causes different physical and mental alterations in the patient. The aesthetic defect and the alteration of the body image can cause important psychological repercussions, especially in adolescence, aggravated by the cult of the body and the obsession with the corporal perfection of today's society. PE causes compression on the heart and lungs. In severe cases, and worsening with age, it causes compression of the right heart chambers and restriction of lung function that can lead to cardiopulmonary disability.
    [0012] There are various techniques and devices for treating PE pathology which are briefly explained below.
    [0014] The devices include a so-called "vacuum bell", designed by engineer E. Klobe in 1992, to treat his own PE. Taking advantage of the elastic capacity of the costal cartilages, he found that, by exerting a vacuum with the bell, it is possible to completely reduce the defect, in a sustainable way over time. It can be used in surgery, as an aid to the intervention, although its greatest usefulness is in the long term, as an orthopedic treatment. The advantage of this treatment with the suction hood is that, in some selected patients, Mild grade and young, can avoid surgical intervention, although it requires a daily follow-up of several years, with frequent non-compliance and recurrences.
    [0016] Regarding the surgical treatment of PE, the aim is to elevate the sternum and the ribs, to avoid the aesthetic defect and the cardiopulmonary compression. There are three classic treatments.
    [0018] 1. - The Ravitch technique, called chondrosternoplasty, constitutes an invasive surgery that was developed by Mark M. Ravitch in 1945. Through a wide skin incision in the anterior part of the thorax, all the costal cartilages near the depression are resected sternal, leaving the perichondrium (outer layer of cartilage). The sternum is fractured outward and is then fixed in the correct position by the fracture line, after which a metal plate is placed behind the sternum to improve fixation and prevent subsidence. The plate must be removed a few years later. This intervention, which is still used today by certain authors, has been partly relegated to less invasive techniques, which allow the defect to be repaired without a scar on the thorax.
    [0020] 2. - The Nuss technique. In 1980, Donald Nuss changed the concept of malformative thoracic surgery with his minimally invasive repair technique (MIRPE) which is now considered the "Gold Standard" for the treatment of PE. As with the suction hood, it takes advantage of rib elasticity for the design of his technique.After introducing a camera into the thoracic cavity, the thorax is crossed with a bar that penetrates through a small hole in the hemithorax and, after passing under the sternum and above the heart, which in In these patients, it is compressed, it is taken out through another hole in the opposite hemithorax, all this directed by videotrascoscopy, to try to avoid perforating the heart. A tape is then placed as a guide that marks the way for the placement of a bar that presents the ideal shape of the corrected thorax, therefore, when it is rotated 180 °, where the sternum sinks, the excavation of the thorax is eliminated. The metal prosthesis is fixed by lateral fixings and it must remain fixed for three years. Once this period is completed, it must be extracted. MIRPE is universally accepted, but it is not exempt from minor and major complications, from 2 to 20%, mainly pain, rotation of the bar, pneumothorax and infection. Despite thoracoscopic control, there is always a risk of cardiac perforation when the rod is inserted between the sternum and the heart. Recently, A. Hebra (2018), in a review, including his cases, between 1998 and 2016, identified 27 published cases and 32 unreported life-threatening complications including: cardiac perforation, hemothorax, major vessel injury, lung injury, liver injury, gastrointestinal problems, and diaphragm injury. There were seven cases of major complications with rod removal (reported and unreported) with two fatal outcomes. There are currently 11 cases of mortality with bar placement surgery: four published death cases and seven unpublished death cases.
    [0022] 3.- Taulinoplasty. Finally, Taulinoplasty, which consists of a correction by inserting an external device into the subcutaneous tissue, was developed by Ventura Medical Technologies together with Dr. Carles Bardají, and offers a less invasive solution. It is an extrathoracic method that apparently reduces the complexity and risks of cardiopulmonary injury, by means of an implant called "Pectus Up Surgery Kit", which is the subject of a European patent validated in Spain with number ES2442740T3, and which is refers to a device for use in the surgical treatment of a patient suffering from a funnel chest, in which the device comprises a plate, adapted to be fitted under the skin of the patient, which has a central part that in use is positioned on top of the sternum, and two lateral parts, which in use are positioned substantially above the ribs, and in which, in addition, the central part comprises at least one hole, adapted to house a fixing element for fixing the plate to the sternum of the patient, and where the curvature, length, and width of the plate are such that, in use, the plate rests on the ribs to support the sternum.
    [0024] To apply the aforementioned implant, it is necessary to make, in the sternum, a hole (see reference 100 in figure 8 of the document) on the structure of the patient's sternum, to place a screw (60), through which we proceed with a vertical traction effort, in the same direction, and opposite direction to that of fixing the aforementioned screw. In this case, the traction effort is confined to a reduced area, generating high traction pressures, which could lead, on certain occasions, that the fixation element, as well as the sternum itself, do not withstand said traction forces and, consequently, a possible sternal rupture, which in theory substantially reduces the effectiveness of the device and of the technique itself. The technique includes a star plate for the introduction of the screws in the sternum that requires a wide skin incision in the midline of the thorax, for its insertion and removal, precisely in the area of the defect, causing a scar of several centimeters. Medium and long-term studies have not been located, but apparently the technique, although it avoids the introduction into the cavity thoracic, can present technical difficulties of implantation and removal and necessarily requires a large scar, unlike the Nuss Technique.
    [0026] Summary description of the invention
    [0028] The present invention largely solves the above-mentioned drawbacks; in particular, by means of a device for use in the surgical treatment of pectus excavatum, which is less invasive than those mentioned in the state of the art, and which avoids penetrating the cardiopulmonary cavities, with minimal skin injury, and with adequate aesthetic results.
    [0030] The device of the invention comprises, as main components, a guide, a curved needle and an optimized correction bar. Specifically, the guide is intended to be supported on the sternum and has two curved channels, while the needle is curved and modified in correspondence with the channels, to be inserted through one of the channels and be extracted through the other channel, penetrating through the sternum between its two cortical plates, without piercing it, and causing an insertion in said sternum. The curved needle houses a wire along the insertion, designed to pull and lift the sternum, correcting the deformation. For its part, the correction bar is intended to be inserted laterally by subcutaneous insertion above the sternum once the wires have been tensioned, to fix them to the bar.
    [0032] The sternum is an odd, middle, and symmetrical bone located in the anterior part of the thorax, measuring approximately 15-20 cm in length, 5 cm in width, and 1 cm in thickness. It consists of two very resistant cortical sheets and, in the center, it presents cancellous trabeculated bone with weaker mechanical properties. In order to carry out an adequate sternal elevation, the device of the invention allows, on the one hand, to firmly hook the sternum and, on the other, to avoid cardiac injury, avoiding going through the sternum, to safely insert the necessary elements, as will be explained later.
    [0034] The advantages of the invention are obvious. Compared to the Nuss technique, a highly satisfactory aesthetic result is achieved, avoiding injuries to the thorax organs and, therefore, risks of complications and even mortality. The reduced dimensions of the bar, and the fact that it is centrally fixed to the sternum, prevent displacement of said bar. Lateral fixation and the use of stabilizers, which is the origin of infections, and lastly, surgical time and expense are reduced, as no thoracoscopy is required and less prosthetic material is used.
    [0036] For its part, in relation to Taulinoplasty, which has in common to avoid cardiopulmonary involvement, the present invention is much less invasive, as well as much superior at an aesthetic level, since it avoids the scar of several centimeters in the midline of the thoracic defect. On the other hand, it achieves a sternal elevation by means of fine wires, which hook a large portion of both sides of the superior cortical plate of the sternum, avoiding the use of the hole made in the sternum, as well as the screw destined to be inserted in said sternum. hole, as described in the "Pectus-Up Surgery Kit" that is anchored in the spongy plate of the sternum, precisely the least resistant portion of the sternum. The present invention uses a small bar modified to the sterno-costal anatomy individually for each patient , very easy to remove, unlike the large stellate plate of Taulinoplasty, which is very difficult to remove, since the screws always provoke a great reactive response in the bone.
    [0038] Brief description of the figures
    [0040] The foregoing and other advantages and characteristics will be more fully understood from the following detailed description, with reference to the accompanying drawings, which are to be considered by way of illustration and not limitation, in which:
    [0042] Figure 1 shows a perspective view of a semi-section of the guide of the device of the invention, fixed to a sternum.
    [0044] Figure 2 shows a semi-sectioned side view of the guide of figure 1 attached to the sternum, where the needle is inserted into the sternum through the guide.
    [0046] Figure 3 shows a schematic view of the wires that traverse the sternum, before being pulled to cause elevation and correct the malformation.
    [0048] Figure 4 shows a schematic view in which the wires have already been pulled to cause elevation and correct the malformation.
    [0050] Figure 5 shows in perspective the correction bar included in the device of the invention.
    [0051] Figure 6 shows the installation of the bar in the thorax, once the malformation has been corrected.
    [0053] Figure 7 shows the result of tying one of the wires while keeping the other taut.
    [0055] Figure 8 shows the result of having tied the two wires.
    [0057] Figure 9 shows a perspective view of the image of Figure 8.
    [0059] Detailed description of a realization example
    [0061] Next, with the aid of the attached figures 1-9 referred to above, a detailed description of a preferred embodiment of a device for use in the treatment of pectus excavatum is given.
    [0063] The device of the invention comprises a guide (1) intended to be fixed to the sternum (2) of a patient (3), and a needle (4) intended to be inserted into the sternum (2) through the guide (1 ).
    [0065] The sternum (2) is a flat bone, but when it is malformed, it tends to be inclined in the horizontal plane. Figures 1-2 show the guide (1). The guide (1) is formed by two separable portions (5), where in Figures 1-2 only one of the portions (5) of the guide (1) has been shown, in order to illustrate the interior. Each of the portions (5) of the guide (1) has: a support body (6) that adapts to the inclination generated by the malformation, remaining parallel to the sternum (2); as well as fixing means (7) to be fixed to the sternum (2), for example, skewers. The guide (1) also comprises two curved channels (8), one at each end, which allow inserting the needle (4) through one of the channels (8) and extracting it through the other channel (8), passing only the bone plate superior cortical bone of the sternum (2) inside and causing an insertion in the sternum (2). Each of the two portions (5) divides the guide (4) in the middle of the channels (8).
    [0067] The needle (4) is curved, in correspondence with the channels (8), so that, when it is inserted into the channels (8), a predefined insertion angle can be generated and, consequently, that the needle (4) has a bony path inside the sternum (2) sufficient to pass through a wide segment of the sternum (2) and, furthermore, that it is impossible to cross it (2) and injure the pericardium. Two insertions are made, with individual needles (4), one on each side of the midline of the sternum (2). The inserts are located in points of greatest decline and oriented in the cranio-caudal direction. The use of the guide (1) avoids the risks associated with insertions that occur without a guide (1), only taking advantage of personal experience, so it can sometimes be insufficient or dangerous, depending on the learning curve. In this sense, the presence of the guide (1) is very useful to avoid cardiac injury, since the angle of the guide through which the needle runs is adapted to the thickness of the sternum (2) to insert the needles (4), It should not be traversed. The needle (4) comprises a first segment, with a tip (15), through which the needle (4) penetrates the sternum (2), as well as a second segment, opposite the first segment, with an increased length with respect to that of the first segment, to facilitate the advancement of the needle (4) inside the guide (1).
    [0069] The needle (4) is configured to carry a respective wire (9), for example, metallic or polyamide, so that, together with the needle (4), each wire (9) passes through the sternum (2) along the insertion. The two portions (5) of the guide (1) are removed after inserting the needle (4), and repositioned before doing the next one, if applicable.
    [0071] Figure 3 illustrates how, with the patient (3) in a supine position, which is the position in which the guide (1) has been fixed to the sternum (2) and the needles (4) have been inserted and the wires housed. (9), a traction force is exerted on the wires (9), to cause an elevation that corrects the malformation of the sternum (2). The elevation is carried out by tensioning the wires (9) with a crane-type device (not represented in the figures), so that the concavity of the sternum (2) is temporarily repaired. Figure 4 illustrates the elevation result. The fact of making two insertions, instead of a single insertion, as well as the fact that the insertions extend in a craniocaudal direction through the interior of the sternum (2), without going through the thickness of the sternum (2), allows the wires (9 ) distribute the traction force necessary to raise the sternum (2) and correct the malformation. Preferably, the needles (4) are not cut, to allow subsequent reuse and extraction of the wire (9), sliding over the bar (10) and at the same point of insertion of the skin.
    [0073] As shown in Figure 5, the device of the invention further includes a correction bar (10). The bar (10) is used to stabilize the correction of the malformation explained above. The bar (10) preferably has a variable cross section. In particular, the bar (10) has a flattened central part (11) and curved ends (12), which preferably have enlarged dimensions with respect to the central part (11). Likewise, preferably, the ends (12) are located slightly inclined and concave, all for a correct adaptation to the upper face of the ribs in the rib cage. The bar (10) also has, in at least one of the ends (12), a hole (13) to facilitate subsequent extraction. The bar (10) can have varied dimensions customized to each patient, depending on the size, and above all, the size of the defect of the sternum (2) of the patient (3). The present invention advantageously reduces the size of the prosthesis considerably in relation to other techniques. This point is essential since the bar (10) is always a foreign body, which will cause fewer side effects at a smaller size. This smaller size opens the doors to using biodegradable bars. In general, dimensions around 15 cm in length, 2 cm in width and 3 mm in thickness can be estimated for an adolescent patient. This same patient would require a bar of about 40 cm if the Nuss technique were used, which would represent a reduction in surgical material of more than 60% when using the present invention. The bar (10) has at least 2 slots (14) to house the wires (9), and a side hole (13) to facilitate removal, as explained below.
    [0075] As can be seen in Figure 6, through a lateral incision of about 2 cm, the bar (10) is introduced through a subcutaneous tunnel, up to the upper surface of the contralateral rib cage. Next, (see figure 7), one of the wires (9) is kept taut, which allows keeping the rib cage in the desired position, while, with the other wire (9), and without removing the needle (4) corresponding, the skin is punctured above the bar (10), to remove the two ends of the wire (9) at a point, to tighten them together and knot them to the bar (10) with a minimal scar, leaving the wires (9 ) housed in the grooves (14) of the bar (10). Next, (see figure 8), the traction of the other wire (9) is released and what was explained above for the other wire (9) is repeated with said wire (9). Next, by means of an incision of a few millimeters, the wire (9) is bent, remaining strongly fixed to the bar (10) and the sternum (2), with the new morphology of the repaired thorax. In this phase, the traction forces on the sternum (2) are distributed between a support with the bar (10) just inserted and fixed, and the traction of two wires (9) that cross a portion of the cortical and cancellous lamina of the sternum (2).
    [0077] The same operation is repeated with the other wire (9), so that the deformity is repaired, since the force necessary for the sternum (2) to sink is completely compensated by the fixation of the bar (10) to the sternum ( 2) at two points and in a wide area, including the cortical and spongy lamina of the sternum (2), and the superior border of the ribs. Figure 9 shows the final result.
    [0079] It is estimated that the bar (10) can be removed later, approximately three years later, by means of the same small incisions, and making use of the lateral hole (13) that it presents in one of the ends. Alternatively, if the bar (10) is constructed of biodegradable materials, its removal will not be necessary.
    [0081] In summary, the combination of the guide (1), the needle (4) and the bar (10), according to the novel device of the invention, improves the currently used devices. The device of the invention, in any of the aforementioned applications, combines high clinical efficacy together with high safety and a very reduced invasive nature, reducing surgical time, making the procedure cheaper, not requiring thoracoscopy, and reducing risks during the procedure itself. intervention, which is of special importance, since the treatment of PE generally has an aesthetic indication, but affects a very relevant area of the thorax, very close to vital organs such as the heart, so providing a technique that is as less invasive as possible it is a very substantial advantage in this type of invention. In the manufacture of the bar (10), medical steel, titanium and modern high resistance biocompatible materials such as BIOPEEK® (polyester-ether-ether-ketone), and optimized biodegradable polymers can be used. The use of this small, customized bar (10), avoiding the use of stabilizers, will reduce cost and secondary effects. Manufacturing with modern biocompatible and biodegradable polymers would make the removal of the bar unnecessary (10) and would avoid a second intervention. The wire (9) can be metallic or made of synthetic material such as Nylon ® (polymers such as polyamides or the like). The guide (1) can be made of metallic or plastic material.
    one
    权利要求:
    Claims (11)
    [1]
    1. - Device for use in the treatment of pectus excavatum, characterized in that it comprises:
    - a guide (1) comprising:
    - at least one support body (6) to rest on the sternum (2) of a patient (3) with a pectus excavatum deformation; and
    - two curved channels (8);
    - At least one needle (4), curved in correspondence with the channels (8), to be inserted through one of the channels (8) and extracted through the other channel (8), penetrating the sternum (2) from the inside , without going through the sternum (2), and causing an insertion in the sternum (2), to accommodate a wire (9), carried by the needle (4), along the insertion, destined to cause elevation and stabilization of the sternum (2), correcting the deformation; and
    - A correction bar (10), intended to be introduced laterally at the subcutaneous level above the sternum (2) once the wires have been tensioned, to fix the wires (9) to the bar (10).
    [2]
    2. - Device for use in treating pectus excavatum, according to claim 1, characterized in that the guide (1) comprises two separable portions (5), where each portion (5) comprises its corresponding support body (6).
    [3]
    3. - Device for use in treating pectus excavatum, according to claim 2, characterized in that each of the two portions (5) divides the guide (1) in half of the channels (8).
    [4]
    4. - Device for use in treating pectus excavatum, according to any of claims 2-3, characterized in that each support body (6) comprises fixing means (7) to be fixed to the sternum (2).
    [5]
    5. - Device for use in the treatment of pectus excavatum, according to any of claims 1-4, characterized in that the needle (4) comprises a first segment, with a tip (15), through which the needle (4) penetrates in the sternum (2), as well as a second segment, opposite the first segment, with an increased length with respect to that of the first segment, to facilitate the advancement of the needle (4) inside the guide (1).
    [6]
    6. Device for use in treating pectus excavatum, according to any of claims 1-5, characterized in that the bar (10) has a variable cross section.
    [7]
    7. Device for use in treating pectus excavatum, according to claim 6, characterized in that the bar (10) has a flattened central part (11) and curved ends (12).
    [8]
    8. - Device for use in treating pectus excavatum, according to claim 7, characterized in that the ends (12) of the bar (10) have enlarged dimensions with respect to the central part (11).
    [9]
    9. - Device for use in treating pectus excavatum, according to any of claims 7-8, characterized in that the bar (10) comprises a hole in at least (13) one of the ends (12).
    [10]
    10. - Device for use in treating pectus excavatum, according to any of claims 6-9, characterized in that the bar (10) comprises at least one central slot (14) to house the wires (9).
    [11]
    11. - Device for use in treating pectus excavatum, according to any of claims 6-10, characterized in that the bar (10) is made of metallic material, polyester-ether-ether-ketone or biodegradable.
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    同族专利:
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    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    EP0583520A1|1992-08-18|1994-02-23|Nauchno-Proizvodstennoe Obiedinenie " Ekran"|Device for treating funnel chest|
    US20040117016A1|2002-11-06|2004-06-17|Horacio Abramson|Apparatus for the correction of chest wall deformities such as pectus carinatum and method of using the same|
    ES2442740T3|2008-08-19|2014-02-13|Corporació Sanitària Parc Taulí|Device for use in the surgical treatment of funnel chest|
    DE102013110415A1|2013-09-20|2015-03-26|Frixit Gmbh & Co. Kg|Targeting device - needle guide|
    WO2016130154A1|2015-02-13|2016-08-18|Biomet Manufacturing, Llc|Rib reconstruction device|
    WO2017157802A1|2016-03-16|2017-09-21|Pampamed Srl|Zip for a rib sternal pull-back system|
    FR2596978A1|1986-04-10|1987-10-16|Peters|BONE FIXING PLATE, PROVIDED WITH SUTURE WIRES|
    KR100504682B1|2002-09-28|2005-08-05|메딕스얼라인 주식회사|implant for the repair of a pectus excavatum|
    GB2537878A|2015-04-29|2016-11-02|Tel Hashomer Medical Res Infrastructure & Services Ltd|Method for application of a suture and suturing guides|
    法律状态:
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    ES201931102A|ES2777423B2|2019-12-11|2019-12-11|SET FOR USE IN TREATMENT OF PECTUS EXCAVATUM|ES201931102A| ES2777423B2|2019-12-11|2019-12-11|SET FOR USE IN TREATMENT OF PECTUS EXCAVATUM|
    PCT/ES2020/070770| WO2021116519A2|2019-12-11|2020-12-07|Assembly for treating pectus excavatum|
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